The metabolome of pink-footed goose: Heavy metals and lipid metabolism

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  • Mette Jensen
  • Rikke Poulsen
  • Langebæk, Rikke
  • Bjørn Munro Jenssen
  • Johanna Moe
  • Tomasz M. Ciesielski
  • Rune Dietz
  • Christian Sonne
  • Jesper Madsen
  • Martin Hansen

Wildlife is exposed to mixtures of environmental contaminants that affect health and population dynamics. Exposure to toxic heavy metals originating from anthropogenic sources may exert metabolic effects at even low exposure concentrations. Here we investigated the relationships between heavy metal exposure and metabolic changes in the migratory bird pink-footed goose (Anser brachyrhynchus). We used blood pellet and blood plasma samples from 27 free-ranging pink-footed geese to study heavy metal (Cd, Cr, Hg, and Pb) exposure in relation to the metabolome. The results relate blood concentrations of Cd (range: 0.218–1.09 ng/g), Cr (range: 0.299–5.60 ng/g), and Hg (range: 2.63–6.00 ng/g) to signal areas of fatty acids and other lipids, while no correlations were identified for Pb level (range: 21.0–64.2 ng/g) exposure. Lipid signal areas were negatively associated with concentrations of Cr and positively associated with Hg exposure (both p < 0.05). α-Linolenic acid and 9-oxononanoic acid were negatively correlated to Cr exposure (both p < 0.05) and were related in the α-linolenic acid metabolism pathway. Compared to known thresholds for aviary species, the heavy metal concentrations are below levels of toxicity, which may explain the low number of metabolites that significantly change. Nevertheless, the heavy metal exposure is still correlated to changes in the lipid metabolism that may reduce migrating birds’ breeding success and increase mortality for an exposed part of the population.

OriginalsprogEngelsk
Artikelnummer116043
TidsskriftEnvironmental Research
Vol/bind231
ISSN0013-9351
DOI
StatusUdgivet - 2023

Bibliografisk note

Funding Information:
The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Rikke Poulsen reports financial support was provided by Horizon 2020). Martin Hansen reports financial support was provided by Horizon 2020).The authors acknowledge the funding support from the Aarhus University Research Foundation (AUFF-T- 2017-FLS-7-4) and the European Union's Horizon 2020 research and innovation program, under grant agreement No. 825753 (ERGO). Senior Engineer Syverin Lierhagen, NTNU, Norway, is acknowledged for performing the HR-ICP-MS analysis. Laboratory technician Kamilla Glendorf, Aarhus University, Denmark, for the support regarding the setup and sample treatment. Lab manager Emil E. Frøkjær, Aarhus University, Denmark, for managing lab and running the samples on the LC-HRMS. Cannon-netting of geese was carried out by a team from Aarhus University and Norwegian partners; the operation was funded by Aarhus University. Permits to catch and handle geese as well as taking blood samples were granted by the Norwegian Animal Welfare Committee Matttilsynet (FOTS ID 13979).

Funding Information:
The authors acknowledge the funding support from the Aarhus University Research Foundation ( AUFF-T- 2017-FLS-7-4 ) and the European Union's Horizon 2020 research and innovation program, under grant agreement No. 825753 (ERGO). Senior Engineer Syverin Lierhagen, NTNU, Norway, is acknowledged for performing the HR-ICP-MS analysis. Laboratory technician Kamilla Glendorf, Aarhus University , Denmark, for the support regarding the setup and sample treatment. Lab manager Emil E. Frøkjær, Aarhus University, Denmark, for managing lab and running the samples on the LC-HRMS. Cannon-netting of geese was carried out by a team from Aarhus University and Norwegian partners; the operation was funded by Aarhus University . Permits to catch and handle geese as well as taking blood samples were granted by the Norwegian Animal Welfare Committee Matttilsynet ( FOTS ID 13979 ).

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© 2023 The Authors

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