TY - ABST

T1 - Center of Rotation of Angulation-based leveling ostetomy fails to restore feline stifle stability in an ex vivo cruciate insufficiency model

AU - Miles, James Edward

AU - Mazdarani, Parisa

N1 - Conference code: 50

PY - 2023

Y1 - 2023

N2 - INTRODUCTION: To determine stifle joint stability following centre of rotation of angulation-based levelling osteotomy (CBLO) of stifles with transected cranial cruciate ligament (CCL) in a novel limb press model.MATERIALS & METHODS: Ten feline hindlimbs were prepared by coxofemoral disarticulation. Quadriceps and gastrocnemius muscles were replaced with turnbuckles in series with load cells. Limbs were mounted in a frame and axially loaded with 30% body weight, and turnbuckles adjusted aiming for a femoral angle of 60° ±2°, and stifle and tibiotarsal angles of 120° ±5°. Limbs were radiographed and contemporaneous load cell measurements taken. This was repeated after CCL transection and again after CBLO to a target tibial plateau angle of 10°. Angles, quadriceps:gastrocnemius force ratios and cranial tibial subluxation were analysed using repeated-measures ANOVA. RESULTS: Cranial tibial subluxation was observed after both CCL transection and CBLO: both were significant compared to the intact joint (p<0.001, 7.1 mm ± 1.2 mm, and p<.001, 6.1 mm ±1.3 mm, respectively). Stability situation did not affect either limb angulation (p>0.4) or force ratios (p=0.2). Mean quadriceps:gastrocnemius force ratio was 2.0 ±0.3. CBLO reduced mean tibial plateau angle from 23.8° to 9.4°.DISCUSSION/CONCLUSION: CBLO failed to restore stifle joint stability despite relatively realistic simulated force ratios.The model has some inadequacies (only two muscles, incorrect muscle force ratios), biomechanical features (muscle-joint lever arms, force orientation), or anatomical differences from the dog (tibial plateau topography). Positioning was repeatable and consistent, and muscle forces were more consistent with in vivo reports than previous feline limb press models.ACKNOWLEDGEMENTS: Institutional funding was received. The authors declare no conflict of interest.

AB - INTRODUCTION: To determine stifle joint stability following centre of rotation of angulation-based levelling osteotomy (CBLO) of stifles with transected cranial cruciate ligament (CCL) in a novel limb press model.MATERIALS & METHODS: Ten feline hindlimbs were prepared by coxofemoral disarticulation. Quadriceps and gastrocnemius muscles were replaced with turnbuckles in series with load cells. Limbs were mounted in a frame and axially loaded with 30% body weight, and turnbuckles adjusted aiming for a femoral angle of 60° ±2°, and stifle and tibiotarsal angles of 120° ±5°. Limbs were radiographed and contemporaneous load cell measurements taken. This was repeated after CCL transection and again after CBLO to a target tibial plateau angle of 10°. Angles, quadriceps:gastrocnemius force ratios and cranial tibial subluxation were analysed using repeated-measures ANOVA. RESULTS: Cranial tibial subluxation was observed after both CCL transection and CBLO: both were significant compared to the intact joint (p<0.001, 7.1 mm ± 1.2 mm, and p<.001, 6.1 mm ±1.3 mm, respectively). Stability situation did not affect either limb angulation (p>0.4) or force ratios (p=0.2). Mean quadriceps:gastrocnemius force ratio was 2.0 ±0.3. CBLO reduced mean tibial plateau angle from 23.8° to 9.4°.DISCUSSION/CONCLUSION: CBLO failed to restore stifle joint stability despite relatively realistic simulated force ratios.The model has some inadequacies (only two muscles, incorrect muscle force ratios), biomechanical features (muscle-joint lever arms, force orientation), or anatomical differences from the dog (tibial plateau topography). Positioning was repeatable and consistent, and muscle forces were more consistent with in vivo reports than previous feline limb press models.ACKNOWLEDGEMENTS: Institutional funding was received. The authors declare no conflict of interest.

M3 - Conference abstract in proceedings

SP - 31

EP - 32

BT - Proceedings of the 50th VOS Conference

T2 - Veterinary Orthopedic Society Conference

Y2 - 11 March 2023 through 18 March 2023

ER -