Prolonged activated prothromboplastin time and breed specific variation in haemostatic analytes in healthy adult Bernese Mountain dogs

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Prolonged activated prothromboplastin time and breed specific variation in haemostatic analytes in healthy adult Bernese Mountain dogs. / Nielsen, Lise; Wiinberg, Bo; Kjelgaard-Hansen, Mads; Jensen, Asger Lundorff; Kristensen, Annemarie Thuri.

I: Veterinary Journal, Bind 190, Nr. 1, 2011, s. 150-153.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Nielsen, L, Wiinberg, B, Kjelgaard-Hansen, M, Jensen, AL & Kristensen, AT 2011, 'Prolonged activated prothromboplastin time and breed specific variation in haemostatic analytes in healthy adult Bernese Mountain dogs', Veterinary Journal, bind 190, nr. 1, s. 150-153. https://doi.org/10.1016/j.tvjl.2010.09.016

APA

Nielsen, L., Wiinberg, B., Kjelgaard-Hansen, M., Jensen, A. L., & Kristensen, A. T. (2011). Prolonged activated prothromboplastin time and breed specific variation in haemostatic analytes in healthy adult Bernese Mountain dogs. Veterinary Journal, 190(1), 150-153. https://doi.org/10.1016/j.tvjl.2010.09.016

Vancouver

Nielsen L, Wiinberg B, Kjelgaard-Hansen M, Jensen AL, Kristensen AT. Prolonged activated prothromboplastin time and breed specific variation in haemostatic analytes in healthy adult Bernese Mountain dogs. Veterinary Journal. 2011;190(1):150-153. https://doi.org/10.1016/j.tvjl.2010.09.016

Author

Nielsen, Lise ; Wiinberg, Bo ; Kjelgaard-Hansen, Mads ; Jensen, Asger Lundorff ; Kristensen, Annemarie Thuri. / Prolonged activated prothromboplastin time and breed specific variation in haemostatic analytes in healthy adult Bernese Mountain dogs. I: Veterinary Journal. 2011 ; Bind 190, Nr. 1. s. 150-153.

Bibtex

@article{8b8b3410e68c11dfb6d2000ea68e967b,
title = "Prolonged activated prothromboplastin time and breed specific variation in haemostatic analytes in healthy adult Bernese Mountain dogs",
abstract = "Coagulation tests are often performed in dogs suspected of haemostatic dysfunction and are interpreted according to validated laboratory reference intervals (RIs). Breed specific RIs for haematological and biochemical analytes have previously been identified in Bernese Mountain dogs, but it remains to be determined if breed specific RIs are necessary for haemostasis tests. Activated prothromboplastin time (aPTT), prothrombin time (PT), selected coagulation factors, D-dimers, fibrinogen, von Willebrand factor and thromboelastography (TEG) were analyzed in healthy Bernese Mountain dogs using the CLSI model.Three analytes (aPTT, TEG [MA] and TEG [G]) were different according to the CLSI model. For aPTT the new RI was markedly different (0-100 s). Whereas the new intervals for TEG (MA) and TEG (G) may be due to breed related biological variation, the cause of the prolonged RI for aPTT is at present uncertain.",
author = "Lise Nielsen and Bo Wiinberg and Mads Kjelgaard-Hansen and Jensen, {Asger Lundorff} and Kristensen, {Annemarie Thuri}",
year = "2011",
doi = "10.1016/j.tvjl.2010.09.016",
language = "English",
volume = "190",
pages = "150--153",
journal = "The Veterinary Journal",
issn = "1090-0233",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Prolonged activated prothromboplastin time and breed specific variation in haemostatic analytes in healthy adult Bernese Mountain dogs

AU - Nielsen, Lise

AU - Wiinberg, Bo

AU - Kjelgaard-Hansen, Mads

AU - Jensen, Asger Lundorff

AU - Kristensen, Annemarie Thuri

PY - 2011

Y1 - 2011

N2 - Coagulation tests are often performed in dogs suspected of haemostatic dysfunction and are interpreted according to validated laboratory reference intervals (RIs). Breed specific RIs for haematological and biochemical analytes have previously been identified in Bernese Mountain dogs, but it remains to be determined if breed specific RIs are necessary for haemostasis tests. Activated prothromboplastin time (aPTT), prothrombin time (PT), selected coagulation factors, D-dimers, fibrinogen, von Willebrand factor and thromboelastography (TEG) were analyzed in healthy Bernese Mountain dogs using the CLSI model.Three analytes (aPTT, TEG [MA] and TEG [G]) were different according to the CLSI model. For aPTT the new RI was markedly different (0-100 s). Whereas the new intervals for TEG (MA) and TEG (G) may be due to breed related biological variation, the cause of the prolonged RI for aPTT is at present uncertain.

AB - Coagulation tests are often performed in dogs suspected of haemostatic dysfunction and are interpreted according to validated laboratory reference intervals (RIs). Breed specific RIs for haematological and biochemical analytes have previously been identified in Bernese Mountain dogs, but it remains to be determined if breed specific RIs are necessary for haemostasis tests. Activated prothromboplastin time (aPTT), prothrombin time (PT), selected coagulation factors, D-dimers, fibrinogen, von Willebrand factor and thromboelastography (TEG) were analyzed in healthy Bernese Mountain dogs using the CLSI model.Three analytes (aPTT, TEG [MA] and TEG [G]) were different according to the CLSI model. For aPTT the new RI was markedly different (0-100 s). Whereas the new intervals for TEG (MA) and TEG (G) may be due to breed related biological variation, the cause of the prolonged RI for aPTT is at present uncertain.

U2 - 10.1016/j.tvjl.2010.09.016

DO - 10.1016/j.tvjl.2010.09.016

M3 - Journal article

C2 - 21035361

VL - 190

SP - 150

EP - 153

JO - The Veterinary Journal

JF - The Veterinary Journal

SN - 1090-0233

IS - 1

ER -

ID: 22884703