Immunometabolic parameters in overweight dogs during weight loss with or without an exercise program

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Standard

Immunometabolic parameters in overweight dogs during weight loss with or without an exercise program. / Vitger, A. D.; Stallknecht, B. M.; Miles, J .E.; Hansen, S. L.; Vegge, A.; Bjørnvad, C. R.

I: Domestic Animal Endocrinology, Bind 59, 04.2017, s. 58-66.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Vitger, AD, Stallknecht, BM, Miles, JE, Hansen, SL, Vegge, A & Bjørnvad, CR 2017, 'Immunometabolic parameters in overweight dogs during weight loss with or without an exercise program', Domestic Animal Endocrinology, bind 59, s. 58-66. https://doi.org/10.1016/j.domaniend.2016.10.007

APA

Vitger, A. D., Stallknecht, B. M., Miles, J. . E., Hansen, S. L., Vegge, A., & Bjørnvad, C. R. (2017). Immunometabolic parameters in overweight dogs during weight loss with or without an exercise program. Domestic Animal Endocrinology, 59, 58-66. https://doi.org/10.1016/j.domaniend.2016.10.007

Vancouver

Vitger AD, Stallknecht BM, Miles JE, Hansen SL, Vegge A, Bjørnvad CR. Immunometabolic parameters in overweight dogs during weight loss with or without an exercise program. Domestic Animal Endocrinology. 2017 apr.;59:58-66. https://doi.org/10.1016/j.domaniend.2016.10.007

Author

Vitger, A. D. ; Stallknecht, B. M. ; Miles, J .E. ; Hansen, S. L. ; Vegge, A. ; Bjørnvad, C. R. / Immunometabolic parameters in overweight dogs during weight loss with or without an exercise program. I: Domestic Animal Endocrinology. 2017 ; Bind 59. s. 58-66.

Bibtex

@article{7bafc8ce7ffe4d4bb9128dda9dcea835,
title = "Immunometabolic parameters in overweight dogs during weight loss with or without an exercise program",
abstract = "The influence of physical activity on metabolic health in overweight dogs is unknown. This study was conducted to evaluate biomarkers of immunometabolic health in relation to changes in physical activity and adiposity. Client-owned overweight dogs participated in a 12-wk intervention based on caloric restriction combined with a training program (fitness and diet [FD] group, n = 8), or caloric restriction alone (diet-only [DO] group, n = 8). Physical activity was monitored by accelerometry. All dogs were fed the same diet and achieved similar weight loss. Fasting blood samples were collected before and after 6- and 12-wk intervention. Insulin resistance was evaluated from plasma insulin and C-peptide as well as homeostasis model assessment. Inflammation and dyslipidemia were evaluated from circulating leptin, adiponectin, C-reactive protein (CRP), monocyte chemoattractant factor-1 (MCP-1), interleukin-8 (IL-8), and cholesterol. Accelerometer counts in both groups were high compared with previous reports of physical activity in overweight dogs. No difference in blood parameters was evident between groups, evaluated by linear mixed-effects model (P > 0.05). Within the groups, the following changes were significant by t-test (P < 0.05): leptin decreased in both groups. Within the FD group, IL-8, MCP-1, and CRP decreased at 6 wk and IL-8 and cholesterol at 12 wk. Within the DO group, C-peptide and HOMA decreased at 6 wk and C-peptide at 12 wk. We conclude that, for both groups, weight loss resulted in minor indications of improved immunometabolic health, whereas this level of physical activity did not add further benefits.",
author = "Vitger, {A. D.} and Stallknecht, {B. M.} and Miles, {J .E.} and Hansen, {S. L.} and A. Vegge and Bj{\o}rnvad, {C. R.}",
note = "Copyright {\textcopyright} 2016 Elsevier Inc. All rights reserved.",
year = "2017",
month = apr,
doi = "10.1016/j.domaniend.2016.10.007",
language = "English",
volume = "59",
pages = "58--66",
journal = "Domestic Animal Endocrinology",
issn = "0739-7240",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Immunometabolic parameters in overweight dogs during weight loss with or without an exercise program

AU - Vitger, A. D.

AU - Stallknecht, B. M.

AU - Miles, J .E.

AU - Hansen, S. L.

AU - Vegge, A.

AU - Bjørnvad, C. R.

N1 - Copyright © 2016 Elsevier Inc. All rights reserved.

PY - 2017/4

Y1 - 2017/4

N2 - The influence of physical activity on metabolic health in overweight dogs is unknown. This study was conducted to evaluate biomarkers of immunometabolic health in relation to changes in physical activity and adiposity. Client-owned overweight dogs participated in a 12-wk intervention based on caloric restriction combined with a training program (fitness and diet [FD] group, n = 8), or caloric restriction alone (diet-only [DO] group, n = 8). Physical activity was monitored by accelerometry. All dogs were fed the same diet and achieved similar weight loss. Fasting blood samples were collected before and after 6- and 12-wk intervention. Insulin resistance was evaluated from plasma insulin and C-peptide as well as homeostasis model assessment. Inflammation and dyslipidemia were evaluated from circulating leptin, adiponectin, C-reactive protein (CRP), monocyte chemoattractant factor-1 (MCP-1), interleukin-8 (IL-8), and cholesterol. Accelerometer counts in both groups were high compared with previous reports of physical activity in overweight dogs. No difference in blood parameters was evident between groups, evaluated by linear mixed-effects model (P > 0.05). Within the groups, the following changes were significant by t-test (P < 0.05): leptin decreased in both groups. Within the FD group, IL-8, MCP-1, and CRP decreased at 6 wk and IL-8 and cholesterol at 12 wk. Within the DO group, C-peptide and HOMA decreased at 6 wk and C-peptide at 12 wk. We conclude that, for both groups, weight loss resulted in minor indications of improved immunometabolic health, whereas this level of physical activity did not add further benefits.

AB - The influence of physical activity on metabolic health in overweight dogs is unknown. This study was conducted to evaluate biomarkers of immunometabolic health in relation to changes in physical activity and adiposity. Client-owned overweight dogs participated in a 12-wk intervention based on caloric restriction combined with a training program (fitness and diet [FD] group, n = 8), or caloric restriction alone (diet-only [DO] group, n = 8). Physical activity was monitored by accelerometry. All dogs were fed the same diet and achieved similar weight loss. Fasting blood samples were collected before and after 6- and 12-wk intervention. Insulin resistance was evaluated from plasma insulin and C-peptide as well as homeostasis model assessment. Inflammation and dyslipidemia were evaluated from circulating leptin, adiponectin, C-reactive protein (CRP), monocyte chemoattractant factor-1 (MCP-1), interleukin-8 (IL-8), and cholesterol. Accelerometer counts in both groups were high compared with previous reports of physical activity in overweight dogs. No difference in blood parameters was evident between groups, evaluated by linear mixed-effects model (P > 0.05). Within the groups, the following changes were significant by t-test (P < 0.05): leptin decreased in both groups. Within the FD group, IL-8, MCP-1, and CRP decreased at 6 wk and IL-8 and cholesterol at 12 wk. Within the DO group, C-peptide and HOMA decreased at 6 wk and C-peptide at 12 wk. We conclude that, for both groups, weight loss resulted in minor indications of improved immunometabolic health, whereas this level of physical activity did not add further benefits.

U2 - 10.1016/j.domaniend.2016.10.007

DO - 10.1016/j.domaniend.2016.10.007

M3 - Journal article

C2 - 27951413

VL - 59

SP - 58

EP - 66

JO - Domestic Animal Endocrinology

JF - Domestic Animal Endocrinology

SN - 0739-7240

ER -

ID: 170088822